A Comprehensive Review on Automated Cardiac Report Generation Using Generative AI

Main Article Content

Sofia Munawar

Abstract

Cardiovascular diseases (CVDs) have been the major cause of death in all parts of the world, with a tremendous burden on healthcare systems. Accurate and timely clinical reporting is essential to diagnosis, treatment planning, and management of patients. Still, the manual generation of reports is time-consuming, prone to error, and not consistently reflective. The use of Generative Artificial Intelligence (AI) and especially transformer-based Large Language Models (LLMs) and multimodal deep learning models offers transformative potential to automate the process of cardiac report generation and improve it. This review focuses on the current state-of-the-art AI-based methods with a focus on semantic understanding, multimodal understanding, and clinical relevance. EchoGPT, MEIT, and ECG-GPT are developed as advanced models that prove it is possible to create human-like clinical narratives, but note the weaknesses of factual accuracy and practical implementation. We present a comparative study of traditional and modern machine learning techniques, comment on the technical, clinical, and ethical issues, and lay out the strategic priorities of further research to enhance reliability, interpretability, and implementation of automated cardiac reporting systems.

Article Details

Munawar, S. (2026). A Comprehensive Review on Automated Cardiac Report Generation Using Generative AI. Journal of Cardiology and Cardiovascular Medicine, 11(3), 19–24. https://doi.org/10.29328/journal.jccm.1001226
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Copyright (c) 2026 Munawar S

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Bhatt CM, Patel P, Ghetia T, Mazzeo PL. Effective heart disease prediction using machine learning techniques. Algorithms. 2023;16(2):88. Available from: https://doi.org/10.3390/a16020088?urlappend=%3Futm_source%3Dresearchgate.net%26utm_medium%3Darticle

Miller RJ, Slomka PJ. Artificial intelligence in nuclear cardiology: an update and future trends. Semin Nucl Med. 2024 Sep;54(5):648-57. Available from: https://doi.org/10.1053/j.semnuclmed.2024.02.005

Srinivasan SM, Sharma V. Applications of AI in cardiovascular disease detection: a review of the specific ways in which AI is being used to detect and diagnose cardiovascular diseases. In: AI Disease Detection: Advanced Applications. 2025. p. 123-46. Available from: https://doi.org/10.1002/9781394278695.ch6

Gibb JJ, Kim WC, Barlatay FG, Tometzki A, Pateman A, Caputo M, et al. Medium-term outcomes of stent therapy for aortic coarctation in children under 30 kg with new generation low-profile stents: a follow-up study of a single centre experience. Pediatr Cardiol. 2024;45(3):544-51. Available from: https://doi.org/10.1007/s00246-023-03402-8

Franke M, Książczyk TM, Dux M, Chmielewski P, Truszkowska G, Czapczak D, et al. A MYH7 variant in a five-generation family with hypertrophic cardiomyopathy. Front Genet. 2024;15:1306333. Available from: https://doi.org/10.3389/fgene.2024.1306333

Bernelli C, Di Fusco SA, Matteucci A, Zilio F, Nesti M, Barbero U, et al. Working in interventional cardiology laboratories: the perceived impact of radiation exposure as a health and gender hazard. A NEXT generation ANMCO initiative. Int J Cardiol. 2024;401:131682. Available from: https://doi.org/10.1016/j.ijcard.2023.131682

Kasartzian DI, Tsiampalis T. Transforming cardiovascular risk prediction: a review of machine learning and artificial intelligence innovations. Life (Basel). 2025;15(1):94. Available from: https://doi.org/10.3390/life15010094

Mathur P, Srivastava S, Xu X, Mehta JL. Artificial intelligence, machine learning, and cardiovascular disease. Clin Med Insights Cardiol. 2020;14:1179546820927404. Available from: https://doi.org/10.1177/1179546820927404

Chowdhury MA, Rizk R, Chiu C, Zhang JJ, Scholl JL, Bosch TJ, et al. The heart of transformation: exploring artificial intelligence in cardiovascular disease. Biomedicines. 2025;13(2):427. Available from: https://doi.org/10.3390/biomedicines13020427

Ali MT, Ali U, Ali S, Tanveer H. Transforming cardiac care: AI and machine learning innovations. Int J Multidiscip Res Growth Eval. 2024. Available from: https://www.allmultidisciplinaryjournal.com/article/2645/transforming-cardiac-care-ai-and-machine-learning-innovations

Tiwari E, Shrimankar D, Maindarkar M, Bhagawati M, Kaur J, Singh IM, et al. Artificial intelligence-based cardiovascular/stroke risk stratification in women affected by autoimmune disorders: a narrative survey. Rheumatol Int. 2025;45(1):14. Available from: https://doi.org/10.1007/s00296-024-05756-5

Chao CJ, Banerjee I, Arsanjani R, Ayoub C, Tseng A, Delbrouck JB, et al. Evaluating large language models in echocardiography reporting: opportunities and challenges. Eur Heart J Digit Health. 2025;6(3):326-39. Available from: https://doi.org/10.1093/ehjdh/ztae086

Wan Z, Liu C, Wang X, Tao C, Shen H, Peng Z, et al. MEIT: multi-modal electrocardiogram instruction tuning on large language models for report generation [Preprint]. arXiv. 2024. Available from: https://doi.org/10.48550/arXiv.2403.04945

Inam M, Sheikh S, Minhas AMK, Vaughan EM, Krittanawong C, Samad Z, et al. A review of top cardiology and cardiovascular medicine journal guidelines regarding the use of generative artificial intelligence tools in scientific writing. Curr Probl Cardiol. 2024;49(3):102387. Available from: https://doi.org/10.1016/j.cpcardiol.2024.102387

Khunte A, Sangha V, Oikonomou EK, Dhingra LS, Aminorroaya A, Coppi A, et al. Automated diagnostic reports from images of electrocardiograms at the point-of-care [Preprint]. medRxiv. 2024. Available from: https://doi.org/10.1101/2024.02.17.24302976

Liu C, Wan Z, Ouyang C, Shah A, Bai W, Arcucci R. Zero-shot ECG classification with multimodal learning and test-time clinical knowledge enhancement [Preprint]. arXiv. 2024. Available from: https://doi.org/10.48550/arXiv.2403.06659

Liu C, Tian Y, Chen W, Song Y, Zhang Y. Bootstrapping large language models for radiology report generation. Proc AAAI Conf Artif Intell. 2024;38(17):18635-43.

Liu T, Krentz A, Lu L, Curcin V. Machine learning-based prediction models for cardiovascular disease risk using electronic health records data: systematic review and meta-analysis. Eur Heart J Digit Health. 2025;6(1):7-22. Available from: https://doi.org/10.1093/ehjdh/ztae080

Zhao C, Xu Z, Baral P, Esposito M, Zhou W. Multi-graph graph matching for coronary artery semantic labeling [Preprint]. arXiv. 2024. Available from: https://doi.org/10.48550/arXiv.2402.15894

Nentidis A, Krithara A, Paliouras G, Krallinger M, Sanchez LG, Lima S, Tutubalina E. BioASQ at CLEF2024: the twelfth edition of the large-scale biomedical semantic indexing and question answering challenge. In: European Conference on Information Retrieval. Cham: Springer Nature Switzerland; 2024. p. 490-97.